This medication is used to treat attention deficit hyperactivity disorder – ADHD. It works by changing the amounts of certain natural substances in the brain. Dextroamphetamine belongs to a class of drugs known as stimulants. It can help increase your ability to pay attention, stay focused on an activity, and control behavior problems. It may also help you to organize your tasks and improve listening skills.
This medication is also used to treat a certain sleeping disorder (narcolepsy) to help you stay awake during the day. It should not be used to treat tiredness or to hold off sleep in people who do not have a sleep disorder.
How to use Dexedrine Tablet
Read the Medication Guide and, if available, the Patient Information Leaflet provided by your pharmacist before you start taking dextroamphetamine and each time you get a refill. If you have any questions, ask your doctor or pharmacist.
Take this medication with or without food as directed by your doctor, usually 1 to 3 times a day. The first dose is usually taken when you wake up in the morning. If more doses are prescribed, take them as directed by your doctor, usually 4-6 hours apart. Taking this medication late in the day may cause trouble sleeping (insomnia).
If you are using the liquid form of this medication, carefully measure the dose using a special measuring device/spoon. Do not use a household spoon because you may not get the correct dose.
The dosage is based on your medical condition and response to treatment. Your doctor may adjust your dose to find the dose that is best for you. Follow your doctor’s instructions carefully.
Use this medication regularly to get the most benefit from it. To help you remember, take it at the same time(s) each day.
During treatment, your doctor may occasionally recommend stopping the medication for a short time to see whether there are any changes in your behavior and whether the medication is still needed.
If you suddenly stop using this medication, you may have withdrawal symptoms (such as severe tiredness, sleep problems, mental/mood changes such as depression). To help prevent withdrawal, your doctor may lower your dose slowly. Withdrawal is more likely if you have used dextroamphetamine for a long time or in high doses. Tell your doctor or pharmacist right away if you have withdrawal.
Though it helps many people, this medication may sometimes cause addiction. This risk may be higher if you have a substance use disorder (such as overuse of or addiction to drugs/alcohol). Do not increase your dose, take it more often, or use it for a longer time than prescribed. Properly stop the medication when so directed.
When this medication is used for a long time, it may not work as well. Talk with your doctor if this medication stops working well.
Tell your doctor if your condition does not improve or if it worsens.
dexedrine Side Effects
Nausea, stomach upset, cramps, loss of appetite, diarrhea, dry mouth, headache, nervousness, dizziness, trouble sleeping, sweating, weight loss, irritability, and restlessness may occur. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.
Remember that your doctor has prescribed this medicine because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
Tell your doctor right away if you have any serious side effects, including: signs of blood flow problems in the fingers or toes (such as coldness, numbness, pain, or skin color changes), unusual wounds on the fingers or toes, mental/mood/behavior changes (such as agitation, aggression, mood swings, depression, hallucinations, abnormal thoughts/behavior, thoughts of suicide), uncontrolled movements, muscle twitching/shaking, outbursts of words/sounds, change in sexual ability/interest, swelling ankles/feet, extreme tiredness, significant unexplained weight loss, frequent/prolonged erections (in males).
Get medical help right away if you have any very serious side effects, including: shortness of breath, chest/jaw/left arm pain, severe headache, fainting, fast/pounding/irregular heartbeat, seizures, weakness on one side of the body, trouble speaking, confusion, blurred vision.
This medication may increase serotonin and rarely cause a very serious condition called serotonin syndrome/toxicity. The risk increases if you are also taking other drugs that increase serotonin, so tell your doctor or pharmacist of all the drugs you take (see Drug Interactions section). Get medical help right away if you develop some of the following symptoms: fast heartbeat, hallucinations, loss of coordination, severe dizziness, severe nausea/vomiting/diarrhea, twitching muscles, unexplained fever, unusual agitation/restlessness.
A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
This is not a complete list of possible side effects. If you notice other effects not listed above, contact your doctor or pharmacist.
Before taking this medication, tell your doctor or pharmacist if you are allergic to it; or to other sympathomimetic drugs (such as amphetamine or lisdexamfetamine); or if you have any other allergies. This product may contain inactive ingredients, which can cause allergic reactions or other problems. Talk to your pharmacist for more details.
Before using this medication, tell your doctor or pharmacist your medical history, especially of: blood circulation problems (such as Raynaud’s disease), certain mental/mood conditions (such as severe agitation, psychosis), personal/family history of mental/mood disorders (such as bipolar disorder, depression, psychotic disorder, suicidal thoughts), heart problems (including irregular heartbeat/rhythm, coronary artery disease, heart failure, cardiomyopathy, problems with the heart structure such as valve problems), family history of heart problems (such as sudden death/irregular heartbeat/rhythm), history of stroke, high blood pressure, overactive thyroid (hyperthyroidism), a certain eye problem (glaucoma), seizures, personal or family history of a substance use disorder (such as overuse of or addiction to drugs/alcohol), personal or family history of uncontrolled muscle movements (such as Tourette’s syndrome).
This drug may make you dizzy. Alcohol or marijuana (cannabis) can make you more dizzy. Do not drive, use machinery, or do anything that needs alertness until you can do it safely. Limit alcoholic beverages. Talk to your doctor if you are using marijuana (cannabis).
Children may be more sensitive to the side effects of this drug, especially weight loss. This medication may slow down a child’s growth. The doctor may recommend temporarily stopping the medication from time to time to reduce this risk. Monitor your child’s weight and height. Consult your doctor or pharmacist for more details.
During pregnancy, this medication should be used only when clearly needed. Discuss the risks and benefits with your doctor. Infants born to mothers who are dependent on this medication may be born too soon (premature) and have low birth weight. They may also have withdrawal symptoms. Tell your doctor right away if you notice possible mood changes, agitation, or unusual tiredness in your newborn.
This medication passes into breast milk and may have undesirable effects on a nursing infant. Therefore, breast-feeding is not recommended while using this drug. Consult your doctor before breast-feeding.
Drug interactions may change how your medications work or increase your risk for serious side effects. This document does not contain all possible drug interactions. Keep a list of all the products you use (including prescription/nonprescription drugs and herbal products) and share it with your doctor and pharmacist. Do not start, stop, or change the dosage of any medicines without your doctor’s approval.
Taking MAO inhibitors with this medication may cause a serious (possibly fatal) drug interaction. Avoid taking MAO inhibitors (isocarboxazid, linezolid, methylene blue, moclobemide, phenelzine, procarbazine, rasagiline, safinamide, selegiline, tranylcypromine) during treatment with this medication. Most MAO inhibitors should also not be taken for two weeks before treatment with this medication. Ask your doctor when to start or stop taking this medication.
Some products have ingredients that could raise your heart rate or blood pressure. Tell your pharmacist what products you are using, and ask how to use them safely (especially cough-and-cold products or diet aids).
The risk of serotonin syndrome/toxicity increases if you are also taking other drugs that increase serotonin. Examples include street drugs such as MDMA/ “ecstasy,” St. John’s wort, certain antidepressants (including SSRIs such as fluoxetine/paroxetine, SNRIs such as duloxetine/venlafaxine), among others. The risk of serotonin syndrome/toxicity may be more likely when you start or increase the dose of these drugs.
This medication may interfere with certain medical/laboratory tests (including blood and urine steroid levels, brain scan for Parkinson’s disease), possibly causing false test results. Make sure laboratory personnel and all your doctors know you use this drug.
If someone has overdosed and has serious symptoms such as passing out or trouble breathing, call 911. Otherwise, call a poison control center right away. US residents can call their local poison control center at 1-800-222-1222. Canada residents can call a provincial poison control center. Symptoms of overdose may include: severe mental/mood changes, seizures, severe/persistent headache, severe restlessness, fast breathing.
Do not share this medication with others. Sharing it is against the law.
Laboratory and/or medical tests (such as blood pressure, heart rate, growth monitoring in children) may be performed periodically to monitor your progress or check for side effects. Consult your doctor for more details.
If you miss a dose, take it as soon as you remember in the morning hours. If it is late in the afternoon or near the time of the next dose, skip the missed dose. Take your next dose at the regular time. Do not double the dose to catch up.
Store at room temperature away from light and moisture. Do not store in the bathroom. Keep all medications away from children and pets.
Do not flush medications down the toilet or pour them into a drain unless instructed to do so. Properly discard this product when it is expired or no longer needed. Consult your pharmacist or local waste disposal company.Information last revised August 2020. Copyright(c) 2020 First Databank, Inc.
Dexedrine Spansule 15 mg Dextroamphetamine Sulfate is the dextro isomer of the compound d,1-amphetamine sulfate, a sympathomimetic amine of the amphetamine group. Chemically, dextroamphetamine is d-alpha-methylphenethylamine, and is present in all forms of DEXEDRINE as the neutral sulfate.
What is Dexedrine?
Dexedrine (generic name: dextroamphetamine sulfate) is a long- or short-acting capsule, taken orally, that is primarily used to treat attention deficit hyperactivity disorder (ADHD or ADD) in children ages 3-12, adolescents, and adults. According to the US. Food and Drug Administration (FDA), Dexedrine is a federally controlled substance (“Schedule II Stimulant”) because it can be abused or lead to dependence. It is an amphetamine.
Dexedrine may improve focus and decrease impulsivity and hyperactive behavior, two hallmark symptoms for some patients with ADHD.
Dexedrine is also used to treat narcolepsy.
Dexedrine Vs. Adderall
Dexedrine is the brand name for dextroamphetamine sulfate; Adderall is the brand name for dextroamphetamine/levoamphetamine salts. Both are stimulant medications prescribed to treat ADHD. They both contain forms of the synthetic compound amphetamine, which is a central nervous system stimulant. The two active forms of the synthetic compound amphetamine are dextro(d)-amphetamine and levo(l)-amphetamine, and d-amphetamine is considered stronger.
Dexedrine contains d-amphetamine, while Adderall contains a 3:1 mixture of immediate-release d-amphetamine and l-amphetamine. Dexedrine and Adderall typically share the same side effects and are classified as Schedule II drugs by the FDA, meaning they carry a high risk of abuse and addiction.
What Is the Best Dosage of Dexedrine?
Short-acting Dexedrine tablets are taken two to three times daily. The tablets are available in 5mg doses. The first dose is typically taken first thing in the morning; tablets should be taken at the same time each day for the best results.
The long-acting Dexedrine capsule is taken once daily, in the morning. 5 mg, 10 mg, and 15 mg doses are available. The time-release formulation is designed to maintain a steady level of medication in your body throughout the day.
As with all medications, follow your Dexedrine prescription instructions exactly. The optimal dosage varies widely by patient; it is not determined by age, weight, or height, but rather by how a person metabolizes the medication.
During treatment, your doctor may periodically ask you to stop taking your Dexedrine so that they can monitor ADHD symptoms; check vital statistics including blood, heart, and blood pressure; or evaluate height and weight. If any problems are found, your doctor may recommend discontinuing treatment.
Some patients report developing a tolerance to Dexedrine after long-term usage. If you notice that your dosage is no longer controlling your symptoms, talk to your doctor to plan a course of action.
Before starting or refilling a Dexedrine prescription, read the medication guide included with your pills, as it may be updated with new information.
This guide should not replace a conversation with your doctor, who has a holistic view of your or your child’s medical history, other diagnoses, and other prescriptions. If you have questions, ask your doctor or pharmacist before you begin taking the medication.
What Are the Side Effects of Dexedrine?
Most people taking Dexedrine do not experience side effects. That said, the most common side effects of Dexedrine are as follows:
- irregular heartbeat
- decreased appetite
- sleep disruptions
- stomach upset
- weight loss
- dry mouth
Serious Side Effects of Dexedrine:
- slowed growth in children
- changes in eyesight
Dexedrine and Driving
Dexedrine may impair your or your teenager’s ability to drive, operate machinery, or perform other potentially dangerous tasks. This side effect usually wears off with time. If side effects are bothersome, or do not go away, talk to your doctor. Most people taking this medication do not experience any of these side effects.
Dexedrine and Heart- or Blood-Pressure Related Problems
Report to your doctor any heart-related problems or a family history of heart and blood pressure problems. Patients with structural cardiac abnormalities and other serious heart problems have experienced sudden death, stroke, heart attack, and increased blood pressure while taking Dexedrine.
Amphetamines can increase blood pressure and heart rate. Physicians should monitor these vital signs closely during treatment. Call your doctor immediately if you or your child experiences warning signs such as chest pain, shortness of breath, or fainting while taking Dexedrine.
Dexedrine and Familial Mental Health
Also disclose to your physician all mental health issues including any family history of suicide, bipolar illness, tics, or depression. The FDA recommends evaluating patients for bipolar disorder, tics, and Tourette’s syndrome prior to stimulant administration.
Dexedrine may create new or exacerbate existing behavior problems, bipolar illness, or Tourette’s syndrome. It can cause psychotic or manic symptoms in children and teenagers. Call your doctor immediately if you or your child experiences new or worsening mental health symptoms including hallucinations or sudden suspicions.
Dexedrine and Circulation Problems
Discuss circulation problems with your doctor before taking Dexedrine, which has been known to cause numbness, coolness, or pain in fingers or toes, including Raynaud’s phenomenon. Report to your doctor any new blood-flow problems, pain, skin color changes, or sensitivities to temperature while taking Dexedrine.
Dexedrine and Substance Abuse
Amphetamines like Dexedrine have a high potential for abuse and addiction, especially among people who do not have ADHD. It is a “Schedule II Stimulant,” a designation that the Drug Enforcement Agency uses for drugs with a high potential for abuse. Other Schedule II drugs include Adderall, Ritalin, and cocaine. People with a history of drug abuse should use caution when trying this medication. Taking the medication exactly as prescribed can reduce potential for abuse.
The above is not a complete list of potential side effects. If you notice any health changes not listed above, discuss them with your doctor or pharmacist.
Who Can Take Dexedrine? Medication Precautions
You should not take Dexedrine if you:
- Have an existing heart condition or hardening of the arteries
- Have high blood pressure
- Have glaucoma
- Are very anxious, tense, or agitated
- Have a history of drug or alcohol abuse
- Have taken a monoamine oxidase inhibitor (MAOI) within 14 days
- Have an allergy to amphetamines, other stimulant medications, or other ingredients in Dexedrine
You should use caution taking Dexedrine if you have mental problems, tics or Tourette’s syndrome, thyroid problems, seizures, or circulation problems.
If you’re thinking of becoming pregnant, discuss the use of Dexedrine with your doctor. Animal studies indicate a potential risk of fetal harm. Dexedrine is passed through breastmilk, so it is recommended that mothers do not nurse while taking it.
Store Dexedrine in a secure place out of the reach of children, and at room temperature. Do not share your Dexedrine prescription with anyone, even another person with ADHD. Sharing prescription medication is illegal, and can cause harm.
What Are the Interactions Associated with Dexedrine?
Before taking Dexedrine, discuss all other active prescription medications with your doctor. Dexedrine can have a dangerous, possibly fatal, interaction with antidepressants including MAOIs.
Exercise caution with medicines that are known to interact with amphetamines including lithium, seizure medications, blood pressure medications, stomach acid medications — like antacids — and cold or allergy medicines that contain decongestants. Even over-the-counter medications may contain ingredients that raise or lower the level of the medication in your blood to a dangerous level. Speak with your doctor about all other prescription and over-the-counter medications you take.
Share a list of all vitamin or herbal supplements, and prescription and non-prescription medications you take with the pharmacist when you fill your prescription, and let all doctors and physicians know you are taking Dexedrine before having any surgery or laboratory tests. The above is not a complete list of all possible drug interact